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style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
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New England Journal <span class=SpellE>lucht</span> <span class=SpellE>haar</span>
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<span class=SpellE>kunnen</span> <span class=SpellE>hebben</span>. De
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class=SpellE>stelden</span>: ‘In 90% van de studies was de <span
class=SpellE>uitkomst</span> <span class=SpellE>gunstig</span> <span
class=SpellE>voor</span> de sponsor van <span class=SpellE>het</span> <span
class=SpellE>geteste</span> <span class=SpellE>geneesmiddel</span>. (…) Op <span
class=SpellE>grond</span> van de <span class=SpellE>tegenstrijdige</span> <span
class=SpellE>bevindingen</span> in <span class=SpellE>gelijkwaardige</span> <span
class=SpellE>vergelijkende</span> studies, <span class=SpellE>blijkt</span> <span
class=SpellE>dat</span> <span class=SpellE>welke</span> <span class=SpellE>onderneming</span>
<span class=SpellE>ook</span> de studies <span class=SpellE>sponsort</span>, <span
class=SpellE><span class=GramE>deze</span></span> <span class=SpellE>altijd</span>
met <span class=SpellE>het</span> <span class=SpellE>betere</span> <span
class=SpellE>antipsychotisch</span> <span class=SpellE>middel</span> <span
class=SpellE>tevoorschijn</span> <span class=SpellE>komt</span>.’ (2)<o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><b style='mso-bidi-font-weight:normal'><span style='font-size:
10.0pt;font-family:Arial'>Weglaten</span></b></span><b style='mso-bidi-font-weight:
normal'><span style='font-size:10.0pt;font-family:Arial'> van <span
class=SpellE>resultaten</span> <o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>Dr. Marcia <span class=SpellE>Angell</span>,
<span class=SpellE>voormalig</span> <span class=SpellE>hoofdredacteur</span>
van de New England Journal of Medicine <span class=SpellE>schreef</span>: ‘<st1:State
w:st="on"><st1:place w:st="on">Kan</st1:place></st1:State> <span
class=SpellE>een</span> <span class=SpellE>farmaceutisch</span> <span
class=SpellE>bedrijf</span> <span class=SpellE>klinisch</span> <span
class=SpellE>onderzoek</span> <span class=SpellE>zó</span> <span
class=SpellE>manipuleren</span> <span class=SpellE>dat</span> <span
class=SpellE>hun</span> <span class=SpellE>producten</span> <span
class=SpellE>beter</span> <span class=SpellE>lijken</span> <span
class=SpellE>dan</span> <span class=SpellE>ze</span> <span class=SpellE>werkelijk</span>
<span class=SpellE>zijn</span>? <span class=SpellE>Helaas</span> is <span
class=SpellE>het</span> <span class=SpellE>antwoord</span> <span
class=SpellE>hierop</span>: ‘<span class=SpellE>ja</span>’. <span
class=SpellE>Klinische</span> studies <span class=SpellE>kunnen</span> op <span
class=SpellE>veel</span> <span class=SpellE>manieren</span> <span
class=SpellE>gemanipuleerd</span> <span class=SpellE>worden</span> en <span
class=SpellE>het</span> <span class=SpellE>gebeurt</span> <span class=SpellE>voortdurend</span>.
<span class=SpellE>Eén</span> <span class=SpellE>manier</span> <span
class=SpellE>om</span> “de <span class=SpellE>dobbelsteen</span> <span
class=SpellE>één</span> <span class=SpellE>kant</span> op <span class=SpellE>te</span>
<span class=SpellE>laten</span> <span class=SpellE>vallen</span>” <span
class=SpellE>bestaat</span> <st1:place w:st="on"><span class=SpellE>erin</span></st1:place>
<span class=SpellE>uitsluitend</span> <span class=SpellE>jonge</span> <span
class=SpellE>proefpersonen</span> <span class=SpellE>te</span> <span
class=SpellE>laten</span> <span class=SpellE>deelnemen</span>, <span
class=SpellE>zelfs</span> <span class=SpellE>wanneer</span> <span
class=SpellE>het</span> <span class=SpellE>te</span> <span class=SpellE>testen</span>
<span class=SpellE>geneesmiddel</span> <span class=SpellE>bedoeld</span> is <span
class=SpellE>voor</span> <span class=SpellE>voornamelijk</span> <span
class=SpellE>oudere</span> <span class=SpellE>personen</span>. <span
class=SpellE>Omdat</span> <span class=SpellE>jonge</span> <span class=SpellE>personen</span>
in <span class=SpellE>het</span> <span class=SpellE>algemeen</span> minder <span
class=SpellE>bijwerkingen</span> <span class=SpellE>vertonen</span>, <span
class=SpellE>zal</span> <span class=SpellE>het</span> <span class=SpellE>geneesmiddel</span>
<span class=SpellE>veiliger</span> <span class=SpellE>lijken</span>.’ (3) <span
class=SpellE>Een</span> <span class=SpellE>andere</span> <span class=SpellE>manier</span>
<span class=SpellE>om</span> <span class=SpellE>uitkomsten</span> <span
class=SpellE>te</span> <span class=SpellE>beïnvloeden</span> is <span
class=SpellE>slechts</span> <span class=SpellE>een</span> <span class=SpellE>deel</span>
van de <span class=SpellE>gegevens</span> <span class=SpellE>te</span> <span
class=SpellE>presenteren</span> en <span class=SpellE>wel</span> <span
class=SpellE>het</span> <span class=SpellE>deel</span> <span class=SpellE>dat</span>
<span class=SpellE>het</span> <span class=SpellE>geneesmiddel</span> <span
class=SpellE>gunstig</span> <span class=SpellE>doet</span> <span
class=SpellE>uitkomen</span>, en de rest <span class=SpellE>te</span> <span
class=SpellE>verzwijgen</span>. <span class=SpellE>Zij</span> <span
class=SpellE>voegt</span> <span class=SpellE>er</span> <span class=SpellE>aan</span>
toe: ‘De <span class=SpellE>meest</span> <span class=SpellE>erge</span> is <span
class=SpellE>het</span> <span class=SpellE>geheel</span> <span class=SpellE>weglaten</span>
van <span class=SpellE>resultaten</span>’. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><b
style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
Arial'>Dr. <span class=SpellE>Angell</span> <span class=SpellE>vervolgt</span>
<o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Slechts</span></span><span
style='font-size:10.0pt;font-family:Arial'> <span class=SpellE>zelden</span> <span
class=SpellE>worden</span> <span class=SpellE>uit</span> <span class=SpellE>academische</span>
<span class=SpellE>kringen</span> <span class=SpellE>hierover</span> <span
class=SpellE>klachten</span> <span class=SpellE>geuit</span>. <span
class=SpellE>Waarom</span>? <span class=SpellE>Omdat</span> <span
class=SpellE>zij</span> <span class=SpellE>zelf</span> <span class=SpellE>hiervan</span>
<span class=SpellE>profiteren</span>. Dr. <span class=SpellE>Angell</span> <span
class=SpellE>schrijft</span>: ‘<st1:place w:st="on"><st1:PlaceName w:st="on">Columbia</st1:PlaceName>
<st1:PlaceType w:st="on">University</st1:PlaceType></st1:place> die de <span
class=SpellE>technologie</span> <span class=SpellE>patenteerde</span> <span
class=SpellE>voor</span> de <span class=SpellE>fabricage</span> van <span
class=SpellE>Epogen</span> en <span class=SpellE>Cerezyme</span>, <span
class=SpellE>ontving</span> <span class=SpellE>bijna</span> 300 <span
class=SpellE>miljoen</span> dollar <span class=SpellE>aan</span> royalties in
<span class=SpellE>het</span> <span class=SpellE>verloop</span> van 17 <span
class=SpellE>jaar</span>. <span class=SpellE>Het</span> patent was <span
class=SpellE>gebaseerd</span> op research die was <span class=SpellE>gesubsidieerd</span>
door de National Institutes of Health (NIH). <span class=SpellE>Dit</span> <span
class=SpellE>betekende</span> <span class=SpellE>dat</span> de <span
class=SpellE>belastingbetaler</span> de <span class=SpellE>rekening</span> <span
class=SpellE>voldeed</span>. <span class=SpellE>Voor</span> Harvard is de <span
class=SpellE>situatie</span> <span class=SpellE>niet</span> <span
class=SpellE>anders</span>. In <span class=SpellE>een</span> deal met <span
class=SpellE>farmaceutische</span> <span class=SpellE>ondernemingen</span> <span
class=SpellE>sloot</span> <span class=SpellE>een</span> Harvard <span
class=SpellE>ziekenhuis</span> <span class=SpellE>een</span> <span
class=SpellE>overeenkomst</span> <span class=SpellE>dat</span> <span
class=SpellE>het</span> <span class=SpellE>farma-bedrijf</span> <span
class=SpellE>Novartis</span> de <span class=SpellE>rechten</span> <span
class=SpellE>verleende</span> op <span class=SpellE>ontdekkingen</span> die <st1:place
w:st="on"><st1:City w:st="on"><span class=SpellE>leiden</span></st1:City></st1:place>
tot <span class=SpellE>nieuwe</span> <span class=SpellE>kankermedicijnen</span>.
<span class=SpellE>Een</span> <span class=SpellE>ander</span> <span
class=SpellE>bedrijf</span>, Merck, <span class=SpellE>bouwde</span> <span
class=SpellE>een</span> <span class=SpellE>twaalf</span> <span class=SpellE>verdiepingen</span>
<span class=SpellE>tellend</span> <span class=SpellE>onderzoeksinstituut</span>
<span class=SpellE>naast</span> <st1:place w:st="on"><st1:PlaceName w:st="on">Harvard</st1:PlaceName>
<st1:PlaceName w:st="on">Medical</st1:PlaceName> <st1:PlaceType w:st="on">School</st1:PlaceType></st1:place>.
<span class=SpellE>Het</span> <span class=SpellE>jaarverslag</span> van <st1:place
w:st="on"><st1:PlaceName w:st="on">Harvard</st1:PlaceName> <st1:PlaceName
w:st="on">Medical</st1:PlaceName> <st1:PlaceType w:st="on">School</st1:PlaceType></st1:place>
<span class=SpellE>vermeldde</span> <span class=SpellE>een</span> <span
class=SpellE>twaalftal</span> <span class=SpellE>farmaceutische</span> <span
class=SpellE>ondernemingen</span> <span class=SpellE>als</span> <span
class=SpellE>begunstigers</span>.’ <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><b
style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
Arial'>Fortune 500 <o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Het</span></span><span
style='font-size:10.0pt;font-family:Arial'> is <span class=SpellE>duidelijk</span>
<span class=SpellE>dat</span> <span class=SpellE>farmaceutische</span> <span
class=SpellE>ondernemingen</span> <span class=SpellE>zich</span> <span
class=SpellE>meer</span> <span class=SpellE>zorgen</span> <span class=SpellE>maken</span>
over <span class=SpellE>winsten</span> <span class=SpellE>dan</span> over <span
class=SpellE>patiënten</span>. De <span class=SpellE>markt</span> van <span
class=SpellE>psychiatrische</span> <span class=SpellE>geneesmiddelen</span>
is <span class=SpellE>een</span> <span class=SpellE>zeer</span> <span
class=SpellE>omvangrijke</span> <span class=SpellE>zakelijke</span> <span
class=SpellE>onderneming</span>. <span class=SpellE>Amerikaanse</span> <span
class=SpellE>artsen</span> <span class=SpellE>schrijven</span> <span
class=SpellE>jaarlijks</span> <span class=SpellE>voor</span> 10 <span
class=SpellE>miljard</span> dollar <span class=SpellE>aan</span> <span
class=SpellE>antipsychotische</span> <span class=SpellE>middelen</span> <span
class=SpellE>voor</span>. ‘De <span class=SpellE>farmaceutische</span> <span
class=SpellE>industrie</span>’, <span class=SpellE>zegt</span> dr. <span
class=SpellE>Angell</span>, ‘is <span class=SpellE>primair</span> <span
class=SpellE>een</span> <span class=SpellE>marketingmachine</span> <span
class=SpellE>voor</span> de <span class=SpellE>verkoop</span> van <span
class=SpellE>geneesmiddelen</span> van <span class=SpellE>dubieus</span> nut.
“Big <span class=SpellE>Pharma</span>” <span class=SpellE>houdt</span> <span
class=SpellE>ons</span> <span class=SpellE>voor</span> de <span class=SpellE>gek</span>.’
En <span class=SpellE>niet</span> <span class=SpellE>zo’n</span> <span
class=SpellE>beetje</span> <span class=SpellE>ook</span>. <span class=SpellE>Wereldwijd</span>
<span class=SpellE>bedraagt</span> de <span class=SpellE>totale</span> <span
class=SpellE>omzet</span> van de <span class=SpellE>farmaceutische</span> <span
class=SpellE>industrie</span> <span class=SpellE>meer</span> <span
class=SpellE>dan</span> 500 <span class=SpellE>miljard</span> dollar per <span
class=SpellE>jaar</span>, de <span class=SpellE>helft</span> <span
class=SpellE>ervan</span> <span class=SpellE>wordt</span> <span class=SpellE>gerealiseerd</span>
in de <span class=SpellE>Verenigde</span> Staten. De <span class=SpellE>winstmarge</span>
<span class=SpellE>bedraagt</span> <span class=SpellE>doorgaans</span> 20% <span
class=SpellE>zodat</span> de <span class=SpellE>gecombineerde</span> <span
class=SpellE>winsten</span> van de <span class=SpellE>tien</span> <span
class=SpellE>geneesmiddelenfabrikanten</span> in de Fortune 500 <span
class=SpellE>méér</span> <span class=SpellE>waren</span> <span class=SpellE>dan</span>
de <span class=SpellE>winsten</span> van de <span class=SpellE>overige</span>
490 <span class=SpellE>ondernemingen</span> <span class=SpellE>samen</span>. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><b style='mso-bidi-font-weight:normal'><span style='font-size:
10.0pt;font-family:Arial'>Voedingssupplementen</span></b></span><b
style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
Arial'> <o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Maar</span></span><span
style='font-size:10.0pt;font-family:Arial'> <span class=SpellE>meer</span> <span
class=SpellE>kassa</span> <span class=SpellE>betekent</span> <span
class=SpellE>niet</span> <span class=SpellE>meer</span> <span class=SpellE>genezingen</span>.
In <span class=SpellE>feite</span>, <span class=SpellE>zo</span> <span
class=SpellE>berichtte</span> de Washington Post: ‘<span class=SpellE>Toen</span>
de <span class=SpellE>federale</span> <span class=SpellE>overheid</span> <span
class=SpellE>onlangs</span> <span class=SpellE>een</span> <span class=SpellE>groot</span>
<span class=SpellE>aantal</span> <span class=SpellE>geneesmiddelen</span> <span
class=SpellE>voor</span> <span class=SpellE>schizofreniepatiënten</span> in <span
class=SpellE>een</span> <span class=SpellE>langdurige</span> <span
class=SpellE>studie</span> <span class=SpellE>vergeleek</span>, <span
class=SpellE>bleek</span> <span class=SpellE>dat</span> de <span
class=SpellE>twee</span> <span class=SpellE>beste</span> <span class=SpellE>middelen</span>
<span class=SpellE>geen</span> patent <span class=SpellE>hadden</span>.’ <span
class=SpellE>Het</span> <span class=SpellE>wordt</span> <span class=SpellE>nog</span>
<span class=SpellE>interessanter</span> <span class=SpellE>wanneer</span> de <span
class=SpellE>lijst</span> <span class=SpellE>wordt</span> <span class=SpellE>uitgebreid</span>
met <span class=SpellE>voeding</span>. Met <span class=SpellE>het</span> <span
class=SpellE>therapeutisch</span> <span class=SpellE>gebruik</span> van <span
class=SpellE>voedingssupplementen</span> <span class=SpellE>gaan</span> de <span
class=SpellE>kosten</span> <span class=SpellE>nog</span> <span class=SpellE>verder</span>
<span class=SpellE>omlaag</span> en <span class=SpellE>het</span> <span
class=SpellE>succes</span> van de <span class=SpellE>behandeling</span> <span
class=SpellE>neemt</span> toe. <span class=SpellE>Volgens</span> <span
class=SpellE>psychiater</span> dr. Abram Hoffer is de <span class=SpellE>orthomoleculaire</span>
<span class=SpellE>therapie</span> <span class=SpellE>vele</span> <span
class=SpellE>malen</span> <span class=SpellE>effectiever</span> <span
class=SpellE>dan</span> de <span class=SpellE>gangbare</span> <span
class=SpellE>therapie</span> met <span class=SpellE>medicijnen</span>. In <span
class=SpellE>voldoende</span> <span class=SpellE>hoge</span> doses <span
class=SpellE>genomen</span>, is <span class=SpellE>niacine</span> (<span
class=SpellE>vitamine</span> B3) de <span class=SpellE>meest</span> <span
class=SpellE>effectieve</span>, <span class=SpellE>goedkoopste</span> en <span
class=SpellE>veiligste</span> <span class=SpellE>behandeling</span> <span
class=SpellE>voor</span> <span class=SpellE>schizofrenie</span> <span
class=SpellE>alsmede</span> <span class=SpellE>voor</span> <span
class=SpellE>een</span> <span class=SpellE>aantal</span> <span class=SpellE>andere</span>
<span class=SpellE>zeer</span> <span class=SpellE>ernstige</span> <span
class=SpellE>mentale</span> <span class=SpellE>aandoeningen</span>. Hoffer en
<span class=SpellE>collega’s</span> <span class=SpellE>toonden</span> <span
class=SpellE>dit</span> reeds <span class=SpellE>tientallen</span> <span
class=SpellE>jaren</span> <span class=SpellE>geleden</span> <span
class=SpellE>aan</span>, in <span class=SpellE>het</span> begin van de <span
class=SpellE>jaren</span> <span class=SpellE>vijftig</span>, <span
class=SpellE>middels</span> de <span class=SpellE>allereerste</span> <span
class=SpellE>dubbelblinde</span> <span class=SpellE>placebogecontroleerde</span>
<span class=SpellE>studie</span> in de <span class=SpellE>geschiedenis</span>
van de <span class=SpellE>psychiatrie</span> met <span class=SpellE>een</span>
<span class=SpellE>voedingsstof</span>. (4) <span class=SpellE>Niacine</span>
is <span class=SpellE>een</span> <span class=SpellE>klinisch</span> <span
class=SpellE>bewezen</span> <span class=SpellE>therapie</span> <span
class=SpellE>voor</span> <span class=SpellE>ernstige</span> <span
class=SpellE>mentale</span> <span class=SpellE>aandoeningen</span> en <span
class=SpellE>toch</span> <span class=SpellE>onthield</span> de <span
class=SpellE>medische</span> <span class=SpellE>professie</span> <span
class=SpellE>haar</span> <span class=SpellE>goedkeuring</span> in de <span
class=SpellE>afgelopen</span> <span class=SpellE>vijftig</span> <span
class=SpellE>jaar</span>. In <span class=SpellE>plaats</span> <span
class=SpellE>daarvan</span> <span class=SpellE>domineren</span> <span
class=SpellE>behandelingen</span> met <span class=SpellE>antipsychotische</span>
<span class=SpellE>middelen</span> <span class=SpellE>het</span> <span
class=SpellE>vakgebied</span>. <span class=SpellE>Maar</span> <span
class=SpellE>deze</span> <span class=SpellE>middelen</span> <span
class=SpellE>voldoen</span> <span class=SpellE>niet</span>. <span
class=SpellE>Een</span> <span class=SpellE>dubbelblinde</span> <span
class=SpellE>studie</span> <span class=SpellE>bij</span> <span class=SpellE>schizofreniepatiënten</span>
<span class=SpellE>toonde</span> <span class=SpellE>aan</span> <span
class=SpellE>dat</span> <span class=SpellE>driekwart</span> van hen <span
class=SpellE>stopte</span> met de <span class=SpellE>farmaceutische</span> <span
class=SpellE>medicatie</span> <span class=SpellE>om</span> <span
class=SpellE>reden</span> van <span class=SpellE>het</span> <span
class=SpellE>niet</span> <span class=SpellE>verdragen</span> <span
class=SpellE>ervan</span> of <span class=SpellE>ruwweg</span> <span
class=SpellE>onvoldoende</span> <span class=SpellE>werkzaamheid</span>. <span
class=SpellE>Dit</span> <span class=SpellE>betekent</span> <span
class=SpellE>dat</span> de <span class=SpellE>bijwerkingen</span> <span
class=SpellE>onverdraaglijk</span> <span class=SpellE>waren</span> of <span
class=SpellE>dat</span> <span class=SpellE>het</span> <span class=SpellE>middel</span>
<span class=SpellE>domweg</span> <span class=SpellE>niet</span> <span
class=SpellE>werkte</span>. (5)<o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><b
style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
Arial'>2,3 <span class=SpellE>miljoen</span> <span class=SpellE>proefpersonen</span>
in de VS per <span class=SpellE>jaar</span> <o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><b
style='mso-bidi-font-weight:normal'><span style='font-size:10.0pt;font-family:
Arial'><o:p> </o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Misschien</span></span><span
style='font-size:10.0pt;font-family:Arial'> <span class=SpellE>zijn</span> <span
class=SpellE>medicijnen</span> <span class=SpellE>niet</span> de <span
class=SpellE>oplossing</span> <span class=SpellE>omdat</span> <span
class=SpellE>mentale</span> <span class=SpellE>aandoeningen</span> <span
class=SpellE>niet</span> <span class=SpellE>veroorzaakt</span> <span
class=SpellE>worden</span> door <span class=SpellE>een</span> <span
class=SpellE>tekort</span> <span class=SpellE>aan</span> <span class=SpellE>medicijnen</span>.
<span class=SpellE>Veel</span> <span class=SpellE>ziekten</span>, in <span
class=SpellE>het</span> <span class=SpellE>bijzonder</span> <span
class=SpellE>mentale</span> <span class=SpellE>aandoeningen</span>, <span
class=SpellE>zouden</span> <span class=SpellE>inderdaad</span> <span
class=SpellE>veroorzaakt</span> <span class=SpellE>kunnen</span> <span
class=SpellE>zijn</span> door <span class=SpellE>voedingstekorten</span> of
de <span class=SpellE>afhankelijkheid</span> van <span class=SpellE>een</span>
<span class=SpellE>bepaalde</span> <span class=SpellE>voedingsstof</span>, <span
class=SpellE>zodat</span> <span class=SpellE>alleen</span> <span
class=SpellE>voedingsstoffen</span> <span class=SpellE>dit</span> <span
class=SpellE>probleem</span> <span class=SpellE>kunnen</span> <span
class=SpellE>corrigeren</span>. <span class=SpellE>Dit</span> is <span
class=SpellE>niet</span> <span class=SpellE>alleen</span> <span class=SpellE><span
class=GramE>logisch</span></span><span class=GramE>,</span> <span
class=SpellE>het</span> is <span class=SpellE>keer</span> op <span
class=SpellE>keer</span> <span class=SpellE>weer</span> <span class=SpellE>gebleken</span>
in <span class=SpellE>klinisch</span> <span class=SpellE>onderzoek</span>. (6)
<span class=SpellE>Vitamines</span> <span class=SpellE>zoals</span> <span
class=SpellE>niacine</span> <span class=SpellE>zijn</span> <span
class=SpellE>goedkoop</span>, <span class=SpellE>veilig</span> en <span
class=SpellE>effectief</span>. De <span class=SpellE>moderne</span> ‘<span
class=SpellE>wondergeneesmiddelen</span>’ <span class=SpellE>zijn</span> <span
class=SpellE>dit</span> <span class=SpellE>allerminst</span>. <span
class=SpellE>Maar</span> <span class=SpellE>ze</span> <span class=SpellE>zijn</span>
<span class=SpellE>winstgevend</span>. <span class=SpellE>Vooral</span> <span
class=SpellE>wanneer</span> de <span class=SpellE>geneesmiddelenfabrikanten</span>
de research, de <span class=SpellE>publiciteit</span> en de <span
class=SpellE>artsen</span> <span class=SpellE>onder</span> <span
class=SpellE>controle</span> <span class=SpellE>hebben</span>. <span
class=SpellE>Geen</span> wonder <span class=SpellE>dat</span> <span
class=SpellE>deze</span> <span class=SpellE>benadering</span> de <span
class=SpellE>meeste</span> <span class=SpellE>bekendheid</span> <span
class=SpellE>geniet</span>. <span class=SpellE>Ons</span> is <span
class=SpellE>zorgvuldig</span> <span class=SpellE>bijgebracht</span> <span
class=SpellE>dat</span> <span class=SpellE>geneesmiddelen</span> <span
class=SpellE>ziekten</span> <span class=SpellE>genezen</span>, <span
class=SpellE>niet</span> <span class=SpellE>voeding</span>. En <span
class=SpellE>zeker</span> <span class=SpellE>niet</span> <span class=SpellE>vitamines</span>.
<span class=SpellE>Het</span> <span class=SpellE>systeem</span> is <span
class=SpellE>goed</span> <span class=SpellE>georganiseerd</span>. <span
class=SpellE>Tegenwoordig</span> <span class=SpellE>doen</span> 2<span
class=GramE>,3</span> <span class=SpellE>miljoen</span> <span class=SpellE>Amerikanen</span>
per <span class=SpellE>jaar</span> <span class=SpellE>dienst</span> <span
class=SpellE>als</span> <span class=SpellE>proefpersoon</span> <span
class=SpellE>waarop</span> <span class=SpellE>farmaceutische</span> <span
class=SpellE>ondernemingen</span> <span class=SpellE>hun</span> <span
class=SpellE>medicijnen</span> <span class=SpellE>uittesten</span>. <span
class=SpellE>Farmaceutische</span> <span class=SpellE>ondernemingen</span> <span
class=SpellE>zetten</span> <span class=SpellE>patiëntenverenigingen</span> op
<span class=SpellE>om</span> <span class=SpellE>specifieke</span> <span
class=SpellE>deelnemers</span> <span class=SpellE>voor</span> <span
class=SpellE>hun</span> <span class=SpellE>klinische</span> studies <span
class=SpellE>te</span> <span class=SpellE>werven</span>. <span class=SpellE>Artsen</span>
<span class=SpellE>ontvangen</span> <span class=SpellE>gemiddeld</span> 7000
dollar <span class=SpellE>voor</span> <span class=SpellE>iedere</span> <span
class=SpellE>patiënt</span> die <span class=SpellE>zij</span> in <span
class=SpellE>een</span> <span class=SpellE>geneesmiddelenonderzoek</span> <span
class=SpellE>betrekken</span>. De <span class=SpellE>farmaceutische</span> <span
class=SpellE>industrie</span> <span class=SpellE>beschikt</span> over <span
class=SpellE>een</span> <span class=SpellE>leger</span> van 88.000 <span
class=SpellE>energieke</span> <span class=SpellE>vertegenwoordigers</span>, <span
class=SpellE>wat</span> <span class=SpellE>er</span> toe <st1:State w:st="on"><span
class=SpellE>kan</span></st1:State> <st1:City w:st="on"><st1:place w:st="on"><span
class=SpellE>leiden</span></st1:place></st1:City> <span class=SpellE>dat</span>
<span class=SpellE>een</span> arts <span class=SpellE>wel</span> <span
class=SpellE>twaalf</span> <span class=SpellE>visites</span> van hen op <span
class=SpellE>één</span> <span class=SpellE>dag</span> <span class=SpellE>te</span>
<span class=SpellE>verwerken</span> <span class=SpellE>krijgt</span>. De <span
class=SpellE>vertegenwoordigers</span> <span class=SpellE>strooien</span> <span
class=SpellE>vaak</span> met <span class=SpellE>cadeautjes</span> en gratis
monsters, <span class=SpellE>zoals</span> <span class=SpellE>Angell</span> <span
class=SpellE>nog</span> <span class=SpellE>eens</span> <span class=SpellE>benadrukt</span>.
(3)<o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><b style='mso-bidi-font-weight:normal'><span style='font-size:
10.0pt;font-family:Arial'>Bijscholing</span></b></span><b style='mso-bidi-font-weight:
normal'><span style='font-size:10.0pt;font-family:Arial'> door <span
class=SpellE>farma</span> <span class=SpellE>betaald</span> <o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Farmaceutische</span></span><span
style='font-size:10.0pt;font-family:Arial'> <span class=SpellE>ondernemingen</span>
<span class=SpellE>betalen</span> <span class=SpellE>bijna</span> <span
class=SpellE>tweederde</span> van de <span class=SpellE>kosten</span> van <span
class=SpellE>bijscholing</span> van <span class=SpellE>artsen</span>. <span
class=SpellE>Hoewel</span> de <span class=SpellE>betrokkenheid</span> van de <span
class=SpellE>farmaceutische</span> <span class=SpellE>industrie</span> <span
class=SpellE>bij</span> de <span class=SpellE>opleiding</span> van <span
class=SpellE>artsen</span> al erg <span class=SpellE>genoeg</span> is, is de <span
class=SpellE>greep</span> op <span class=SpellE>het</span> <span
class=SpellE>geneesmiddelenonderzoek</span> <span class=SpellE>schandalig</span>.
<span class=SpellE>Zo</span> is <span class=SpellE>bijvoorbeeld</span> de <span
class=SpellE>publicatiestrategie</span> van <span class=SpellE>een</span> <span
class=SpellE>farmaceutische</span> <span class=SpellE>onderneming</span> <span
class=SpellE>als</span> <span class=SpellE>volgt</span>. <span class=SpellE>Angell</span>:
‘<span class=SpellE>marginaal</span> <span class=SpellE>onderzoek</span> <span
class=SpellE>wordt</span> <span class=SpellE>gesponsord</span>, <span
class=SpellE>een</span> <span class=SpellE>artikel</span> <span class=SpellE>wordt</span>
<span class=SpellE>erover</span> <span class=SpellE>geschreven</span> en <span
class=SpellE>vervolgens</span> <span class=SpellE>worden</span> <span
class=SpellE>academische</span> <span class=SpellE><span class=GramE>onderzoekers</span></span>
<span class=SpellE>betaald</span> <span class=SpellE>om</span> <span
class=SpellE>hun</span> <span class=SpellE>naam</span> <span class=SpellE>erboven</span>
<span class=SpellE>te</span> <span class=SpellE>zetten</span>’. De <span
class=SpellE>situatie</span> is <span class=SpellE>zó</span> <span
class=SpellE>slecht</span> <span class=SpellE>dat</span> dr. <span
class=SpellE>Angell</span> <span class=SpellE>er</span> <span class=SpellE>een</span>
<span class=SpellE>redactioneel</span> <span class=SpellE>artikel</span> in
de New England Journal of Medicine <span class=SpellE>aan</span> <span
class=SpellE>wijdde</span> met <span class=SpellE>als</span> kop: ‘Is de <span
class=SpellE>Academische</span> <span class=SpellE>Geneeskunde</span> <span
class=SpellE>te</span> koop?’7 <span class=SpellE>Een</span> <span
class=SpellE>lezer</span> <span class=SpellE>antwoordde</span> <span
class=SpellE>zuur</span>: ‘Nee, de <span class=SpellE>huidige</span> <span
class=SpellE>eigenaar</span> is <span class=SpellE>er</span> heel <span
class=SpellE>gelukkig</span> <span class=SpellE>mee</span>’. <span
class=SpellE>Het</span> <span class=SpellE>resultaat</span>? ‘<span
class=SpellE>Vooroordeel</span> is <span class=SpellE>tegenwoordig</span> <span
class=SpellE>schering</span> en <span class=SpellE>inslag</span> <span
class=SpellE>bij</span> <span class=SpellE>het</span> <span class=SpellE>geneesmiddelenonderzoek</span>.
(…) Door <span class=SpellE>farmaceutische</span> <span class=SpellE>ondernemingen</span>
<span class=SpellE>gefinancierde</span> research <span class=SpellE>bleek</span>
<span class=SpellE>bijna</span> <span class=SpellE>vier</span> <span
class=SpellE>maal</span> <span class=SpellE>zo</span> <span class=SpellE>vaak</span>
<span class=SpellE>gunstig</span> <span class=SpellE>uit</span> <span
class=SpellE>te</span> <span class=SpellE>vallen</span> <span class=SpellE>voor</span>
<span class=SpellE>het</span> product van de <span class=SpellE>onderneming</span>
<span class=SpellE>dan</span> research <span class=SpellE>welke</span> was <span
class=SpellE>gesubsidieerd</span> door de NIH.3 <span class=SpellE>Bedenk</span>
<span class=SpellE>wel</span>, <span class=SpellE>gesubsidieerd</span> door
de NIH <span class=SpellE>betekent</span> ‘<span class=SpellE>gefinancierd</span>
door de <span class=SpellE>belastingbetaler</span>’. En <span class=SpellE>vervolgens</span>,
<span class=SpellE>wanneer</span> <span class=SpellE>deze</span> <span
class=SpellE>een</span> <span class=SpellE>medicijn</span> <span
class=SpellE>nodig</span> <span class=SpellE>heeft</span>, <span
class=SpellE>betaalt</span> <span class=SpellE>dezelfde</span> <span
class=SpellE>belastingbetaler</span> <span class=SpellE>opnieuw</span> en <span
class=SpellE>veel</span> <span class=SpellE>teveel</span> <span class=SpellE>voor</span>
<span class=SpellE>het</span> <span class=SpellE>geneesmiddel</span> <span
class=SpellE>dat</span> door <span class=SpellE>subsidiegelden</span> <span
class=SpellE>bekostigd</span> <span class=SpellE>werd</span> <span
class=SpellE>om</span> <span class=SpellE>het</span> <span class=SpellE>te</span>
<span class=SpellE>kunnen</span> <span class=SpellE>ontwikkelen</span>. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><span style='font-size:10.0pt;font-family:Arial'>Wat</span></span><span
style='font-size:10.0pt;font-family:Arial'> <span class=SpellE>een</span>
prima <span class=SpellE>systeem</span> <span class=SpellE>voor</span> de <span
class=SpellE>farmaceutische</span> <span class=SpellE>industrie</span>. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
class=SpellE><b style='mso-bidi-font-weight:normal'><span style='font-size:
10.0pt;font-family:Arial'>Referenties</span></b></span><b style='mso-bidi-font-weight:
normal'><span style='font-size:10.0pt;font-family:Arial'>:<o:p></o:p></span></b></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>1. <span class=SpellE>Vedantam</span>
S. Drug studies skewed toward study sponsors. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>Industry-funded research often
favors patent-holders, study finds. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>The <st1:State w:st="on"><st1:place
w:st="on">Washington</st1:place></st1:State> Post, 11 April 2006 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>2. <span class=SpellE>Heres</span>
S, Davis <span class=GramE>J ,</span> [..], <span class=SpellE>Leucht</span>
S. Why <span class=SpellE>Olanzapine</span> Beats <span class=SpellE>Risperidone</span>,
<span class=SpellE>Risperidone</span> Beats <span class=SpellE>Quetiapine</span>,
and <span class=SpellE>Quetiapine</span> Beats <span class=SpellE>Olanzapine</span>:
An Exploratory Analysis of Head-to-Head Comparison Studies of Second-Generation
Antipsychotics. Am J Psychiatry 2006; 163:185-94 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>3. <span class=SpellE>Angell</span>
M. The Truth about the Drug Companies. <st1:State w:st="on"><st1:place w:st="on">New
York</st1:place></st1:State>. Random House, 2004 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>4. Hoffer A. Healing
Schizophrenia. Complementary Vitamin & Drug <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>Treatments. <st1:State w:st="on"><st1:place
w:st="on">Ontario</st1:place></st1:State>, CCNM Press: 2004
[http://www.doctoryourself. <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>com/review_hoffer_B3.html]; Hoffer
A. Vitamin B-3 and Schizophrenia: Discovery, Recovery, <span class=GramE>Controversy</span>.
Quarry Press, <st1:place w:st="on"><st1:City w:st="on">Kingston</st1:City>, <st1:State
w:st="on">Ontario</st1:State> <st1:country-region w:st="on">Canada</st1:country-region></st1:place>:
1998 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>[ <a
href="http://www.doctoryourself.com/review_hoffer_B3.html">http://www.doctoryourself.com/review_hoffer_B3.html</a>
] <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>5. Stroup TS, Lieberman JA, [<span
class=GramE>..]</span>, Hsiao JK. Effectiveness of <span class=SpellE>olanzapine</span>,
<span class=SpellE>quetiapine</span>, <span class=SpellE>risperidone</span>,
and <span class=SpellE>ziprasidone</span> in patients with chronic
schizophrenia following discontinuation of a previous atypical antipsychotic.
Am J Psychiatry 2006; 163(4):611-22 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>6. Stroup TS, <span class=SpellE>McEvoy</span>
JP, [<span class=GramE>..]</span> , Lieberman JA. The National Institute of
Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness
(CATIE) project: schizophrenia trial design and protocol development. <span
class=SpellE>Schizophr</span> Bull 2003; 29(1):15-31 <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>7. <span class=SpellE>Angell</span>
M. Is academic medicine for sale? N <span class=SpellE>Engl</span> J Med
2000; <o:p></o:p></span></p>
<p class=MsoNormal style='tab-stops:0in .5in 1.0in 1.5in 2.0in 2.5in 3.0in 3.5in 4.0in 4.5in 5.0in 5.5in 6.0in right 6.5in'><span
style='font-size:10.0pt;font-family:Arial'>342(20):1516-8 <o:p></o:p></span></p>
<b style='mso-bidi-font-weight:normal'><span style='font-size:12.0pt;
font-family:Arial;mso-fareast-font-family:"Times New Roman";mso-ansi-language:
EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA'><br clear=all
style='mso-special-character:line-break;page-break-before:always'>
</span></b>
<p class=MsoNormal><span style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:10.0pt;font-family:Arial'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:10.0pt;font-family:Arial'>(Reprinted
with permission from Saul AW. <span class=SpellE>Gemanipuleerd</span> <span
class=SpellE>klinisch</span> <span class=SpellE>onderzoek</span>. [Manipulated
clinical research] <i style='mso-bidi-font-style:normal'>Orthomolecular Magazine</i>,
2009. <span class=SpellE>Vol</span> 27, No. 2, p 66-68. Dutch. <a
href="http://www.ortho.nl/">www.ortho.nl</a> <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>For more nutritional
therapy information, you might want to read <i>DOCTOR YOURSELF</i> (<a
href="http://www.doctoryourself.com/saulbooks.html">http://www.doctoryourself.com/saulbooks.html</a>)
and <i>FIRE YOUR DOCTOR!</i> (<a
href="http://www.doctoryourself.com/review.html">http://www.doctoryourself.com/review.html</a>)
<br>
<o:p></o:p></span></p>
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