1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
|
<html xmlns:v="urn:schemas-microsoft-com:vml"
xmlns:o="urn:schemas-microsoft-com:office:office"
xmlns:w="urn:schemas-microsoft-com:office:word"
xmlns:st1="urn:schemas-microsoft-com:office:smarttags"
xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv=Content-Type content="text/html; charset=windows-1252">
<meta name=ProgId content=Word.Document>
<meta name=Generator content="Microsoft Word 11">
<meta name=Originator content="Microsoft Word 11">
<link rel=File-List href="mccormick_files/filelist.xml">
<link rel=Edit-Time-Data href="mccormick_files/editdata.mso">
<!--[if !mso]>
<style>
v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style>
<![endif]-->
<title>mccormick</title>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="country-region"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="State"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="City"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="place"/>
<!--[if gte mso 9]><xml>
<w:WordDocument>
<w:ValidateAgainstSchemas/>
<w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid>
<w:IgnoreMixedContent>false</w:IgnoreMixedContent>
<w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText>
<w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel>
</w:WordDocument>
</xml><![endif]--><!--[if gte mso 9]><xml>
<w:LatentStyles DefLockedState="false" LatentStyleCount="156">
</w:LatentStyles>
</xml><![endif]--><!--[if !mso]><object
classid="clsid:38481807-CA0E-42D2-BF39-B33AF135CC4D" id=ieooui></object>
<style>
st1\:*{behavior:url(#ieooui) }
</style>
<![endif]-->
<style>
<!--
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{mso-style-parent:"";
margin:0in;
margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:12.0pt;
font-family:"Times New Roman";
mso-fareast-font-family:"Times New Roman";}
a:link, span.MsoHyperlink
{color:blue;
text-decoration:underline;
text-underline:single;}
a:visited, span.MsoHyperlinkFollowed
{color:purple;
text-decoration:underline;
text-underline:single;}
p
{font-size:12.0pt;
font-family:"Times New Roman";
mso-fareast-font-family:"Times New Roman";}
@page Section1
{size:8.5in 11.0in;
margin:1.0in 1.25in 1.0in 1.25in;
mso-header-margin:.5in;
mso-footer-margin:.5in;
mso-paper-source:0;}
div.Section1
{page:Section1;}
-->
</style>
<!--[if gte mso 10]>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:"Table Normal";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-parent:"";
mso-padding-alt:0in 5.4pt 0in 5.4pt;
mso-para-margin:0in;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:"Times New Roman";
mso-ansi-language:#0400;
mso-fareast-language:#0400;
mso-bidi-language:#0400;}
</style>
<![endif]-->
<meta name=keywords content="health, natural">
<meta name=Template content="C:\Program Files\Microsoft Office\Office\html.dot">
<!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="2050"/>
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1"/>
</o:shapelayout></xml><![endif]-->
<!-- ADD style1 ===================== -->
<style type="text/css">
#TFlag
{
float:right;
font-size:105%;
line-height:105%;
padding:.15 em;
margin:.15 em;
}
img.top
{
vertical-align:text-top;
}
</style>
<!-- END ADD style1 ===================== -->
</head>
<body bgcolor=white background=Image1.gif lang=EN-US link=blue vlink=purple
style='tab-interval:.5in'>
<!-- ADD TFlag ===================== -->
<span id ="TFlag">
<a href="#translator_block">
Click here to translate this page.
<img class="top" SRC="images/TranslateFlag.jpg" alt="translate gadget at page bottom" height=36>
</a>
</span>
<!-- END ADD TFlag ===================== -->
<div class=Section1>
<p> </p>
<table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=621
style='width:465.75pt;mso-cellspacing:0in'>
<tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes;mso-yfti-lastrow:yes'>
<td width="21%" style='width:21.0%;padding:.75pt .75pt .75pt .75pt'>
<p><img width=117 height=105 id="_x0000_i1025" src="images/logo1.GIF"></p>
</td>
<td width="3%" style='width:3.0%;padding:.75pt .75pt .75pt .75pt'>
<p> </p>
</td>
<td width="58%" style='width:58.0%;padding:.75pt .75pt .75pt .75pt'>
<p><img width=365 height=60 id="_x0000_i1026" src="images/dystitle2.JPG"><br>
<img width=365 height=20 id="_x0000_i1027" src="images/dysaut.JPG"></p>
</td>
<td width="18%" style='width:18.0%;padding:.75pt .75pt .75pt .75pt'>
<p><b><span style='font-family:Arial'>Megadose Vitamin C: Dr. William J.
McCormick</span></b></p>
</td>
</tr>
</table>
<div class=MsoNormal align=center style='text-align:center'>
<hr size=2 width="100%" align=center>
</div>
<table class=MsoNormalTable border=0 cellspacing=0 cellpadding=0 width=732
style='width:549.0pt;mso-cellspacing:0in'>
<tr style='mso-yfti-irow:0;mso-yfti-firstrow:yes'>
<td width="19%" valign=top style='width:19.48%;padding:.75pt .75pt .75pt .75pt'>
<p><span style='color:red'>Dr. W. McCormick </span> <br>
<a href="index.html">Home</a></p>
</td>
<td width="2%" style='width:2.54%;padding:.75pt .75pt .75pt .75pt'>
<p> </p>
</td>
<td width="77%" valign=top style='width:77.98%;padding:.75pt .75pt .75pt .75pt'>
<p style='margin:0in;margin-bottom:.0001pt'><b style='mso-bidi-font-weight:
normal'><span style='font-family:Arial'>MEGADOSES OF VITAMIN C AND DR.
WILLIAM J. McCormick<o:p></o:p></span></b></p>
<p style='margin:0in;margin-bottom:.0001pt'><b style='mso-bidi-font-weight:
normal'><span style='font-family:Arial'>by Andrew W. Saul<o:p></o:p></span></b></p>
<p><i><span style='font-size:10.0pt;font-family:Arial'>(This paper originally
was published as "The Pioneering Work of William J. McCormick, MD"
in the Journal of Orthomolecular Medicine, Vol. 18, No. 2, 2003, p 93-96. It
is reprinted here with permission.)<o:p></o:p></span></i></p>
<p><st1:City w:st="on"><st1:place w:st="on"><span style='font-size:11.0pt;
font-family:Arial'>Darwin</span></st1:place></st1:City><span
style='font-size:11.0pt;font-family:Arial'> had a far easier time with the
acceptance of evolution than orthomolecular physicians have had gaining
acceptance of the therapeutic use of ascorbic acid.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>It takes vitamin C to
make collagen and strong connective tissue. That fact is in every nutrition
textbook ever written. It has also been shown that vitamin C supplementation
enhances collagen synthesis. (1) And does so rapidly, too. (2) But few know
that, some 50 years ago, it was Toronto physician William J. McCormick, M.D.,
who pioneered the idea that poor collagen formation, due to vitamin C
deficiency, was a principal cause of diverse conditions ranging from stretch
marks to cardiovascular disease and cancer.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>STRETCH MARKS<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>In 1948, Dr. McCormick
(3) wrote:<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"[T]hese disfiguring
subdermal lesions, which for centuries were regarded as a natural sequence of
pregnancy, are the result of increased fragility of the involved abdominal
connective tissue, secondary to deficiency of vitamin C." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>The strength of a brick
wall is not truly in the bricks, for a stack of bricks can easily be pushed
apart. Collagen is the "mortar" that binds your cells together,
just as mortar binds bricks together. If collagen is abundant and strong,
body cells hold together well. It is possible to see how this property would
prevent stretch marks.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>CANCER<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>It is a logical but large
step to propose that, if cells stick together, tumors would have a tough time
spreading through them. Irwin Stone (4) credited McCormick with taking that
very step:<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"In cancer, the
maintenance of collagen synthesis at optimal levels, may provide such tough
and strong tissue ground substance around any growing cancer cells so that
they would be firmly anchored and could not break away and metastasize."<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>This simple theory would
be the foundation for Linus Pauling and Ewan Cameron's decision to employ
large doses of vitamin C to fight cancer. After all, if cancer cells are
going to try to metastasize, it makes sense to provide abundant vitamin C to
strengthen collagen to keep them from doing so. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Dr. McCormick was among
the first to comment that persons with cancer typically have exceptionally
low levels of vitamin C in their tissues, a deficiency of approximately 4,500
mg. This could help explain why a cancer patient's collagen is generally not
tough enough to be able to prevent cancer from spreading. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'> McCormick also
thought that the symptoms of classic vitamin C deficiency disease, scurvy,
closely resemble the symptoms of some types of leukemia and other forms
cancer. Today, although scurvy is generally considered to be virtually
extinct, cancer is all too prevalent. If the signs of development of cancer
and scurvy are similar, could they be fundamentally the same disease under
different names? In his 1962 paper "Have We Forgotten the Lesson of
Scurvy" (5) Dr. McCormick writes: <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"As long ago as
1609, Martini cited by (scurvy research pioneer Dr. James) Lind stated that
scurvy is nearly allied to the plague, as it occasions carbuncles, buboes and
cancer. In an effort to clarify this relationship we published two papers
(6,7) in which we advanced the hypothesis that deficiency of vitamin C, by
bringing about disintegration of epithelial and connective tissue relationships,
owing to liquefaction of the intercellular cement substance collagen) and
disintegration of the connective tissue of the basement membrane, results in
breakdown of orderly cellular arrangement, thus acting as a prelude to
cancer." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>He also cites this obscure
but interesting reference in the 1905 edition of Northnagel's Encyclopedia of
Practical Medicine (8) which describes the scorbutic aspects of acute
lymphatic leukemia: "The most striking clinical symptoms of this disease
are the hemorrhages and their sequelae. . . Every touch produces hemmorhage,
making a condition completely identical with that of scurvy."<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Dr. McCormick's
conclusion is that <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"Our major effort
(against cancer) should be directed toward prevention of the cause of the
cellular disarrangement - collagenous breakdown of epithelial and
subepithelial connective tissues - as manifested in open sores or fissures
that fail to heal readily, and unusual or easily produced hemorrhage. Such
lesions may be early warning signs of future cancer. They likewise are early
signs of scurvy." (p. 10) <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>If our civilization is
suffering from a scurvy epidemic under the current name of cancer, then the
symptoms, progress and results of the two diseases may have a common cause
(vitamin C deficiency) and a common treatment: vitamin C in large quantity.
If this is even partially true, then all cancer patients should receive large
doses of ascorbic acid as a matter of routine.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>CARDIOVASCULAR DISEASE<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>As scorbutic gum tissue
spontaneously hemorrhages, so also a scorbutic artery can literally
"bleed" into itself. McCormick, over twenty years before Linus
Pauling, reviewed the nutritional causes of heart disease and noted that four
out of five coronary cases in hospital show vitamin C deficiency. In one
paper (9) he wrote that, as early as 1941,<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"<st1:City w:st="on"><st1:place
w:st="on">Paterson</st1:place></st1:City> (10) called attention to the low
vitamin-C status of coronary thrombosis cases. He found that 81 per cent of
such cases in hospital practice had a subnormal blood-plasma level as
compared to 55.8 per cent in a corresponding group of general public ward
patients. He attributes the precipitation of thrombosis to a prior subintimal
capillary hemorrhage at the site of the lesion, which he has verified at
autopsy. He regards this hemorrhagic prelude as due to C-avitaminosis and
suggests that patients with this disease be assured of an adequate intake of
this vitamin." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>And while the exact
meaning of the word "adequate" has been at the heart of nutrition
controversy ever since, supplementation with even a moderate quantity of vitamin
C has been shown to prevent disease and save lives. Just 500 mg daily results
in a 42 percent lower risk of death from heart disease and a 35 percent lower
risk of death from any cause. (11)<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>VITAMIN C AS ANTIBIOTIC
AND ANTIVIRAL<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Dr. McCormick proposed
vitamin C deficiency as the essential cause of, and an effective cure for,
numerous communicable illnesses. In "The Changing Incidence and
Mortality of Infectious Disease in Relation to Changed Trends in
Nutrition" (12) McCormick cited mortality tables as early as 1840, and
suggested that tuberculosis, diphtheria, scarlet fever, whooping cough,
rheumatic fever and typhoid fever are primarily due to inadequate dietary
vitamin C. It remains as novel an idea today as it was nearly 60 years ago to
say that disease trends in history might be understood as waves of lack of
vitamin C intake. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Dr. McCormick considered
vitamin C to be the pivotal therapeutic nutrient "by reason of its
chemical action as a reducing agent, and sometimes as an oxidizing agent,
vitamin C is also a specific antagonist of chemical and bacterial
toxins." Furthermore, in "Ascorbic Acid as a Chemotherapeutic
Agent" (13) he stated: <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"Vitamin C is known
to play an essential part in the oxidation-reduction system of tissue
respiration and to contribute to the development of antibodies and the
neutralization of toxins in the building of natural immunity to infectious
diseases. There is a very potent chemotherapeutic action of ascorbic acid
when given in massive repeated doses, 500 to 1,000 mg. (hourly), preferably
intravenously or intramuscularly. When thus administered the effect in acute
infectious processes is favorably comparable to that of the sulfonamides or
the mycelial antibiotics, but with the great advantage of complete freedom
from toxic or allergic reactions." (p. 151) <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>There is considerable
evidence that vitamin C in large, frequent doses can cure what are usually
called infectious diseases. To establish that these diseases are actually
vitamin C deficiency diseases, we should be able to prevent them by regular,
abundant supply of the vitamin. This is exactly what can be done, McCormick
said: <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"Once the acute
febrile or toxic stage of an infectious disease is brought under control by
massive ascorbic acid administration, a relatively small maintenance dose of
the vitamin will be adequate in most cases to prevent relapses, just as in
fire protection small chemical extinguishers may be adequate to prevent fires
in their incipiency, whereas when large fires have developed, water from large
high-pressure fire hoses becomes necessary." (p. 152) <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Along with his
contemporary, Frederick R. Klenner, M.D., McCormick was an early advocate of
using vitamin C as an antiviral and an antibiotic. Klenner would go on to use
much larger quantities (350-700 mg per kg body weight per day). In the
1950's, even McCormick's relatively modest four or five daily 1,000-2,000 mg
doses were perceived as astronomically high, and something to be feared.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>In some minds, this
remains the case today.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>KIDNEY STONES<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Ever since Linus Pauling
began publicizing the value of megadoses of vitamin C in the early 1970's, it
has been a cornerstone of medical mythology that vitamin C can cause kidney
stones. The accusation is false. (14) Everybody has heard about unicorns and can
describe one in detail. You could probably draw a unicorn. You can see one in
your mind right now. Yet unicorns do not exist. They are imaginary, without
substance or proof. Just like a vitamin C kidney stone. The vitamin C kidney
stone myth is the best known non-fact in non-existence. Every physician has
heard of one, but <i>not one of them has ever seen one. </i>That is because
they simply do not exist.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'> As Dr Abram Hoffer
has said, "Contrary to popular medical belief, vitamin C does not cause
kidney stones; at least it never has so far. Maybe in it will in the next
1000 years." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Writers often pass by the
fact that Dr. McCormick actually advocated vitamin C to prevent and cure the
formation of some kidney stones as far back as 1946 (15), when he wrote: <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"I have observed
that a cloudy urine, heavy with phosphates and epithelium, is generally
associated with a low vitamin C status. . . and that as soon as corrective
administration of the vitamin effects a normal ascorbic acid (vitamin C)
level the crystalline and organic sediment disappears like magic from the
urine. I have found that this change can usually be brought about in a matter
of hours by large doses of the vitamin, 500 to 2,000 mg, oral or
parenteral." (p. 411) <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>In what might be seen as
a display of almost too much therapeutic versatility, Dr. McCormick affirmed
that calculi in other parts of the body could be cleared up by plenty of
vitamin C, including stones in the biliary tract, the pancreas, tonsils,
appendix, mammary glands, uterus, ovaries, prostate and "even the
calcareous deposits in arteriosclerosis." He said that calcareous
deposits in the eye "may be cleared away in a few days by correction of
vitamin C status, and I find also that dental calculus (tartar on the teeth),
which lays the foundation for so much dental havoc, can be quickly suppressed
and prevented by an adequate intake of vitamin C." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Odd though this final
statement may seem, "there appears to be a very real correlation between
vitamin C state (as a possible nonmechanical contributor) and debris
irrespective of tooth cleansing habits," wrote Professor of Oral
Medicine Emanuel Cheraskin, M.D., D.M.D., in 1993. (16) Dr. Cheraskin cited a
clinical trial that "reported a resolution of materia alba, calculus,
and stain when 500 mg of ascorbic acid was daily administered for 90
days." <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>CIGARETTE SMOKING<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Fifty years ago,
McCormick (17) wrote:<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>"The writer has
found, in clinical and laboratory research, that the smoking of one cigarette
neutralizes in the body approximately 25 mg of ascorbic acid, or the
equivalent of the vitamin C content of one average-size orange. On this
basis, the ability of the heavy smoker to maintain normal vitamin C status
from dietary sources is obviously questionable, and this alone may account
for the prevalence of vitamin C deficiency in our modern adult
population."<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>This was quite a
statement in 1954, at a time when physicians were literally endorsing their
favorite cigarette in magazines and on television commercials. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>No doubt it is purely
coincidental that calculii, cigarettes, cancer, cardiovascular disease,
connective tissue, and collagen all have the letter "C" in common.
William J. McCormick's lifetime of work helped establish that these words
also have a vitamin in common. Dr. McCormick fought vitamin C deficiency
wherever his clinical experience found it. His early use of gram-sized doses
to combat what then and now are usually regarded as non-deficiency-related
illnesses set the stage for today's 100,000 mg/day antiviral/anticancer
vitamin C IV's. For such a good idea, the spread of this knowledge to date
has been exceptionally slow. Without McCormick's published work, it might
never have spread at all.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>REFERENCES:<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(1) Chan D, Lamande SR,
Cole WG, Bateman JF. (1990) Regulation of procollagen synthesis and processing
during ascorbate-induced extracellular matrix accumulation in vitro. Biochem
J. Jul 1; 269(1):175-81<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(2) Franceschi RT, Iyer
BS, Cui Y. (1994) Effects of ascorbic acid on collagen matrix formation and
osteoblast differentiation in murine MC3T3-E1 cells. J Bone Miner Res. Jun;
9(6):843-54.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(3) McCormick, W J (1948)
The striae of pregnancy: A new etiological concept. Medical Record. August. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(4) Stone, I The genetic
disease, hypoascorbemia: A fresh approach to an ancient disease and some of
its medical Implications. Acta Geneticae Medicae et Gemellologiae, Volume 16,
Number 1, 1967, pp. 52-60<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(5) McCormick, W J (1962)
Have we forgotten the lesson of scurvy? Journal of Applied Nutrition. 15(1,2)
p 4-12. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(6) McCormick, W J
(1954a) Cancer: The preconditioning factor in pathogenesis. Archives of
Pediatrics of <st1:State w:st="on"><st1:place w:st="on">New York</st1:place></st1:State>.
71:313. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(7) McCormick, W J
(1959). Cancer: A collagen disease, secondary to a nutritional deficiency?
Arch. Pediat., 76: 166.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(8) Pincus, F (1905)
Acute lymphatic leukemia. In: Nothnagel's Encyclopedia of Practical Medicine,
American Edition. <st1:City w:st="on"><st1:place w:st="on">Philadelphia</st1:place></st1:City>:
W.B. Saunders & Co., p 552-574.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(9) McCormick, W J (1957)
Coronary thrombosis: a new concept of mechanism and etiology. Clinical
Medicine. 4:7, July. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(10) Paterson, J. C.;
Some factors in the causation of intimal hemorrhage and in the precipitation
of coronary thrombosis, Can. Med. Assoc. J. 44: 114, 1941.<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(11) Enstrom, J E et al.
Vitamin C intake and mortality among a sample of the <st1:country-region
w:st="on"><st1:place w:st="on">United States</st1:place></st1:country-region>
population. Epidemiology, Vol. 3, No. 3, May 1992, pp. 194-202 <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(12) McCormick, W J
(1947) The changing incidence and mortality of infectious disease in relation
to changed trends in nutrition. Medical Record. September. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(13) McCormick, W J
(1952) Ascorbic acid as a chemotherapeutic agent. Archives of Pediatrics of <st1:State
w:st="on"><st1:place w:st="on">New York</st1:place></st1:State>. 69:151-155,
April. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(14) Intake of vitamins
B6 and C and the risk of kidney stones in women. Curhan, G. C., Willett, W.
C., Speizer, F. E., Stampfer, M. J. J Am Soc Nephrol 10:4:840-845, Apr 1999<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(15) McCormick, W J
(1946) Lithogenesis and hypovitaminosis. Medical Record. 159:7, July, p
410-413)<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(16) The Case of the
Invisible Toothbrush: Why Some People Can Brush Less by E. Cheraskin, M.D.,
D.M.D. <i>Journal of Orthomolecular Medicine</i> Vol. 8, No. 3, 1993)<o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>(17) McCormick, W J (1954b)
Intervertebral disc lesions: a new etiological concept. Archives of
Pediatrics of <st1:State w:st="on"><st1:place w:st="on">New York</st1:place></st1:State>.
71:29-33, January. <o:p></o:p></span></p>
<p><span style='font-size:11.0pt;font-family:Arial'>Locating William J.
McCormick's papers is now somewhat easier than it used to be because a number
of them have been posted on the Internet. at </span><span style='font-size:
11.0pt'><a href="http://www.seanet.com/~alexs/ascorbate/"><span
style='font-family:Arial'>http://www.seanet.com/~alexs/ascorbate/</span></a></span><span
style='font-size:11.0pt;font-family:Arial'> and also here at </span><span
style='font-size:11.0pt'><a href="http://www.doctoryourself.com/"><span
style='font-family:Arial'>http://www.doctoryourself.com</span></a></span><span
style='font-size:11.0pt;font-family:Arial'> .<o:p></o:p></span></p>
<p><o:p> </o:p></p>
</td>
</tr>
<tr style='mso-yfti-irow:1'>
<td width="19%" style='width:19.48%;padding:.75pt .75pt .75pt .75pt'>
<p align=center style='text-align:center'><a href="contact.html"><span
style='text-decoration:none;text-underline:none'><img border=0 width=55
height=60 id="_x0000_i1029" src="images/e-mail.gif"></span></a><br>
<a href="contact.html">Andrew W. Saul</a></p>
</td>
<td width="2%" style='width:2.54%;padding:.75pt .75pt .75pt .75pt'>
<p> </p>
</td>
<td width="77%" style='width:77.98%;padding:.75pt .75pt .75pt .75pt'>
<div class=MsoNormal align=center style='text-align:center'>
<hr size=2 width="100%" align=center>
</div>
<p><span style='font-size:7.5pt'>AN IMPORTANT NOTE: This page is not in
any way offered as prescription, diagnosis nor treatment for any disease,
illness, infirmity or physical condition. Any form of self-treatment or
alternative health program necessarily must involve an individual's
acceptance of some risk, and no one should assume otherwise. Persons
needing medical care should obtain it from a physician. Consult your
doctor before making any health decision. </span> </p>
<p><span style='font-size:7.5pt'>Neither the author nor the webmaster has
authorized the use of their names or the use of any material contained within
in connection with the sale, promotion or advertising of any product or
apparatus. Single-copy reproduction for individual, non-commercial use is
permitted providing no alterations of content are made, and credit is given.</span>
</p>
<div class=MsoNormal align=center style='text-align:center'>
<hr size=2 width="100%" align=center>
</div>
<p class=MsoNormal></p>
</td>
</tr>
<tr style='mso-yfti-irow:2;mso-yfti-lastrow:yes'>
<td width="19%" style='width:19.48%;padding:.75pt .75pt .75pt .75pt'>
<p> </p>
</td>
<td width="2%" style='width:2.54%;padding:.75pt .75pt .75pt .75pt'>
<p> </p>
</td>
<td width="77%" style='width:77.98%;padding:.75pt .75pt .75pt .75pt'>
<p align=center style='text-align:center'><span style='font-size:10.0pt;
font-family:Arial'>| </span><a href="index.html"><span
style='font-size:10.0pt;font-family:Arial'>Home</span></a><span
style='font-size:10.0pt;font-family:Arial'> | </span><a
href="order.html"><span style='font-size:10.0pt;font-family:
Arial'>Order my Books</span></a><span style='font-size:10.0pt;font-family:
Arial'> | </span><a href="aboutme.html"><span
style='font-size:10.0pt;font-family:Arial'>About the Author</span></a><span
style='font-size:10.0pt;font-family:Arial'> | </span><a
href="contact.html"><span style='font-size:10.0pt;font-family:
Arial'>Contact Us</span></a><span style='font-size:10.0pt;font-family:Arial'>
| </span><a href="webmaster.html"><span style='font-size:10.0pt;
font-family:Arial'>Webmaster</span></a><span style='font-size:10.0pt;
font-family:Arial'> |</span></p>
</td>
</tr>
</table>
<p class=MsoNormal><o:p> </o:p></p>
</div>
<!-- ADD TBlock1 ===================== -->
<a name="translator_block"></a>
<br>
<div id="MicrosoftTranslatorWidget" style="width: 200px; min-height: 0px; border-color: #3A5770; background-color: #78ADD0;">
<noscript>
<a href="http://www.microsofttranslator.com/bv.aspx?a=http%3a%2f%2fwww.doctoryourself.com%2f">
Translate this page
</a>
<br />
Powered by
<a href="http://www.microsofttranslator.com">
Microsoft® Translator
</a>
</noscript>
</div>
<script type="text/javascript">
/* <![CDATA[ */
setTimeout(function()
{ var s = document.createElement("script");
s.type = "text/javascript"; s.charset = "UTF-8";
s.src = "http://www.microsofttranslator.com/Ajax/V2/Widget.aspx?mode=manual&from=en&layout=ts";
var p = document.getElementsByTagName('head')[0] || document.documentElement;
p.insertBefore(s, p.firstChild); }, 0);
/* ]]> */
</script>
<br>
<!-- ===================== -->
<!-- Use this block only in a REPLACE statement : it contains extra characters ! -->
<!-- ===================== -->
<!-- Note: -must- "escape" the "</body>" in the s.src line on find-and-replace ===================== -->
<!-- END ADD TBlock1 ===================== -->
</body>
</html>
|
